Changing status of XMRV / HGRV research

I expect that Next Generation Sequencing or NGS, which does not have the flaws of PCR technology in evaluating a poorly understood human virus(es), will be the best way forward to a consensus as to the question of association of CFS with XMRV/HGRV.

GcMAF studies presented at IACFS/ME meetings in Ottawa

GcMAF appears to be an effective therapy for well defined CFS partients

Review of stem cell therapy results as of September 2010 – a public announcement

Stem cell therapy as of September 2010 is briefly reviewed in over 25 patients treated to date in Panama by SCI.

A second publication links CFS even closer to a novel family of retroviruses – What do we call them?

On the 23rd of August 2010, a PNAS on-line publication (Lo et al) was published out of the NIH and the FDA confirming Judy Mikovits’ October 2009 Science papers’ assertion that a Mouse Leukemia Virus (MLV)-related retrovirus (RV) is strongly linked to CFS.

Stem cell results as of April 2010

We are now close to 20 CFS patients who have received stem cell transfusions primarily in Panama at SCI and coming up on 8 with 12-18 months of follow-up in June.  We have three functional cures (KPS of 75-80) both clinically and by ETM, all under 36 years of age (N=3). A KPS of 75 [...]

Stem cell results in a family of three seven months out from treatment

The Cheney Clinic has now treated 13 CFS patients with stem cells over the past year. Results appear very promising to date but treatment notably includes significant adjuvant therapy including anti-XMRV treatment strategies and cell signaling factors as well as gut modification therapies. This brief report details the results of a family of three with CFS.

Nine-month post-stem cell follow-up results

I recently saw my longest follow-up stem cell patient at nine months out from stem cell treatment. This 57 yr old medically retired nurse was a KPS of 40 prior to stem cell therapy and an invalid with basic ADL assistance provided by her husband in the three months prior to stem cells given in early February 2009. She was essentially bed or couch bound and quite ill at times. Today, nine months later, I estimate her KPS at 65 as she notes she could now live alone and can engage in hobbies but could not at present work a regular part-time job.

A retrovirus called XMRV is linked to CFS

The finding of antibody or active virus in 95% of CFS and 4% of controls is a result that argues for causality, in my opinion, especially with the associated RNAse-L corruption and NK functional impairment that might predict such an infection. This novel retrovirus could easily shift the redox state just like HIV as published in (2001) and (1995) and induce all manner of associated pathogens as seen in CFS,,,,. A redox shift could ultimately corrupt the gut ecology and create P450 decoupling based on NADPH depletion observed in CFS and lead to environmental illness as well. Time will tell but I think Dr. Mikovits is right to suspect causality. I also think this virus is infectious with at least ten million Americans infected who appear healthy and perhaps another four million Americans or more with CFS as recently estimated by the CDC (2007). However, disease expression may be more limited causing the illusion that it is not infectious. Furthermore, there may be other diseases that are similar and dissimilar to CFS that are associated with if not caused by XMRV.

The best EFA ratio for CFS consumption – an atypical and surprising choice

In this post, we explore the incredible finding that different ratios of omega-3 to omega-6 EFA’s appear to produce dramatically different effects on the echocardiographically derived ETM, both positive and negative. Surprisingly, the use of omega-3 EFA’s and especially fish oil is uniformly negative (N=10) in CFS but not in controls (N=3). This is not terribly surprising since omega-3 oils are far more easily oxidized and is possibly explained by the more redox impaired status of CFS. However, we are also finding that omega-6 alone, while better than omega-3 alone in an oxidizing state such as CFS, is not nearly as positive as a mixture of the omega-3, omega-6 and omega-9 EFA’s. In particular, a ratio of omega-6 to omega-3 of 3:1 appears ideal and generates the most positive ETM response. Such a ratio is found in high grade olive oil but not lower grades of olive oil which are as high as 13:1, omega-6 over omega-3.

Gut Dysbiosis Modulates Significant CFS Symptoms

A recent publication from both Kenny DeMeirleir and Australian investigators has important implications regarding the management of gut dysbiosis.  The bottom line is that they showed increased bacterial overgrowth in the GI tract in CFS that produces bacterial derived D-Lactate that is likely responsible for significant cognitive problems, especially memory.   There is also a high [...]

Cheney Clinic Book

Dr. David Bell has been commissioned by an independent party to write a book on research at the Cheney clinic that it has been engaged in since 2004. There will be emphasis on the clinic’s work in the field of echocardiography and an in-depth analysis by Dr. Bell of Dr. Cheney’s understanding of Chronic [...]

The Cheney Clinic Website!

The Cheney Clinic is proud to announce the debut of its new, state of the art web site. A free to the public front-end allows prospective patients to peruse the clinic and what it can offer them including treatment philosophy, clinic policies, contact information and information which we hope will allow an informed decision [...]

CheneyResearch.com – New Research Website!

The Cheney Clinic will soon launch a premium web site to display and comment on emerging research both at this clinic and in other research areas pertinent to CFS. The new web site will be at www.cheneyresearch.com and will contain the most up-to-date public talks, powerpoint slides, research abstracts and blog commentary on CFS [...]

Stem Cells Update at The Cheney Clinic

The Cheney Clinic has now treated eight CFS patients in recent months using adult stem cells derived from the afterbirth of normal, healthy new-born infants. This current research direction is an outgrowth of the clinic’s research efforts over the last nine years using cell associated therapies which can broadly adjust the biological terrain. [...]